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TCR gamma/delta 抗体

This anti-TCR gamma/delta antibody is a Armenian Hamster 单克隆 antibody detecting TCR gamma/delta in FACS, IP 和 IHC (f). Suitable for 小鼠. This Primary Antibody has been cited in 11+ publications.
产品编号 ABIN2689517
发货至: 中国

Quick Overview for TCR gamma/delta 抗体 (ABIN2689517)

抗原

TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))

适用

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小鼠

宿主

  • 39
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  • 1
Armenian Hamster

克隆类型

  • 62
单克隆

标记

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This TCR gamma/delta antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

UC7
  • 品牌

    BD Pharmingen™

    产品特性

    The UC7-13D5 antibody reacts with the γδ T-cell Receptor (TCR) complex on γδ TCR-expressing T lymphocytes and NK-T cells of all mouse strains tested. It does not react with the αβ TCR-bearing T cells. In the mouse, cell expressing the γδ TCR are found in the thymus, intestinal epithelium, epidermis, dermis, pulmonary epithelium, peritoneum, liver, and peripheral lymphoid organs. Plate-bound UC7-13D5 antibody activates γδ TCR-bearing T cells, and in vivo administration of the mAb depletes peripheral γδ TCR-bearing T cells. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

    BD Pharmingen™ Purified Hamster Anti-Mouse γδ T-Cell Receptor - Purified - Clone UC7-13D5 - Isotype Armenian Hamster IgG3, κ - Reactivity Ms - 0.5 mg

    纯化方法

    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

    免疫原

    Not Reported

    亚型

    IgG3 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Aqueous buffered solution containing protein stabilizer and ≤0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store undiluted at 4°C.
  • King, Hyde, Jackson, Novosad, Ellis, Putney, Stovall, Van Winkle, Beaman, Ferrick: "Cutting edge: protective response to pulmonary injury requires gamma delta T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 9, pp. 5033-6, (1999) (PubMed).

    Shinohara, Ikarashi, Maruoka, Miyata, Sugimura, Terada, Wakasugi: "Functional and phenotypical characteristics of hepatic NK-like T cells in NK1.1-positive and -negative mouse strains." in: European journal of immunology, Vol. 29, Issue 6, pp. 1871-8, (1999) (PubMed).

    Tamaki, Yasaka, Chang, Ohtake, Saitoh, Nakamura, Furue: "Identification and characterization of novel dermal Thy-1 antigen-bearing dendritic cells in murine skin." in: The Journal of investigative dermatology, Vol. 106, Issue 3, pp. 571-5, (1996) (PubMed).

    van der Heyde, Elloso, Chang, Kaplan, Manning, Weidanz: "Gamma delta T cells function in cell-mediated immunity to acute blood-stage Plasmodium chabaudi adami malaria." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 8, pp. 3985-90, (1995) (PubMed).

    Kaufmann, Blum, Yamamoto: "Crosstalk between alpha/beta T cells and gamma/delta T cells in vivo: activation of alpha/beta T-cell responses after gamma/delta T-cell modulation with the monoclonal antibody GL3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 20, pp. 9620-4, (1993) (PubMed).

    Skeen, Ziegler: "Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 971-84, (1993) (PubMed).

    Hiromatsu, Yoshikai, Matsuzaki, Ohga, Muramori, Matsumoto, Bluestone, Nomoto: "A protective role of gamma/delta T cells in primary infection with Listeria monocytogenes in mice." in: The Journal of experimental medicine, Vol. 175, Issue 1, pp. 49-56, (1992) (PubMed).

    Bluestone, Cron, Barrett, Houlden, Sperling, Dent, Hedrick, Rellahan, Matis: "Repertoire development and ligand specificity of murine TCR gamma delta cells." in: Immunological reviews, Vol. 120, pp. 5-33, (1991) (PubMed).

    Lefrancois: "Phenotypic complexity of intraepithelial lymphocytes of the small intestine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 6, pp. 1746-51, (1991) (PubMed).

    MacDonald, Schreyer, Howe, Bron: "Selective expression of CD8 alpha (Ly-2) subunit on activated thymic gamma/delta cells." in: European journal of immunology, Vol. 20, Issue 4, pp. 927-30, (1990) (PubMed).

    Tigelaar, Lewis, Bergstresser: "TCR gamma/delta+ dendritic epidermal T cells as constituents of skin-associated lymphoid tissue." in: The Journal of investigative dermatology, Vol. 94, Issue 6 Suppl, pp. 58S-63S, (1990) (PubMed).

  • 抗原

    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))

    别名

    Gammadelta T-Cell Receptor
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